Optimal glycemic control in neurocritical care patients: a systematic review and meta-analysis. Initial studies will need to refine safer approaches to intensive blood sugar control with closed loop and GLPbased approacheswhile the identification of patient groups for stratified blood glucose targets evolves from CER analyses of ongoing studies. Blinding of outcome assessment was only considered relevant when neurological outcome was assessed. Three studies did not provide details on allocation concealment. DOC kb. The heterogeneity in glycaemic targets may potentially obscure any between-group outcome effects.
The cornerstone of the management of TBI is the intensive care treatment. Even unconscious TBI patients may have increased blood pressure and ICP. Conversely, cooling may be neuroprotective and has been seen to. the benefits and harms of treating high blood pressure in TBI patients.
. or SBP > mmHg) being at higher risk for in-hospital mortality. High-volume trauma centers have better outcomes treating traumatic brain injury. The association between admission systolic blood pressure and mortality in Pre-hospital tracheal intubation in patients with traumatic brain injury: .
Propofol: neuroprotection in an in vitro model of traumatic brain injury.
Thereafter a reminder was sent and a reply awaited for a further 4 weeks. J Trauma. After a while, I wanted to be better informed about the prospects. Again, the research is still in early stages and results are based on animal testing.
Guidelines for the management of severe traumatic brain injury, Fourth Edition. The marked heterogeneity in defining infective complications precluded formal meta-analysis.
In this review, we evaluated previous studies of neuroprotection and found that Department of Neurology, Xinqiao Hospital, The Army Medical . blood supply with animal stroke models except for lacking of high risk factors.
Neuroprotection influencing the progression of the disease; 3. Metab Brain Dis.
All of the poor neurological outcome scores include death. Crit Care Med. Functional level during the first 2 years after moderate and severe traumatic brain injury. Intensive versus conventional glucose control in critically ill patients with traumatic brain injury: long-term follow-up of a subgroup of patients from the NICE-SUGAR study.
The BTF and EBIC advocate a mean blood pressure (MBP) of >90 mm Hg. Hypothermia has been shown to be neuroprotective in animal studies. Numerous methodological problems have been raised with regard to.
multiple reported neuroprotective actions, including enhancing cerebral blood flow and.
Video: Neuroprotection in icu with high blood ICU Brain Trauma Management Part 1 (Step 2 and 3)
Although there has been significant progress in the area of medical and surgical thrombolytic technologies, neuroprotective agents to prevent secondary.
The indirect estimates for liberal versus moderate control were 0.
ICU mortality. The first category is well taken care off in the Netherlands.
Three studies did not provide details on allocation concealment. A comprehensive overview of blood glucose control focussed on the TBI population has never been performed and there are no contemporary guidelines for the optimal glycaemic range in this population [ 15 ]. For me, it is currently not an option.